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Maladaptive Modulations of NLRP3 Inflammasome and Cardioprotective Pathways Are Involved in Diet-Induced Exacerbation of Myocardial Ischemia/Reperfusion Injury in Mice

Excessive fatty acids and sugars intake is known to affect the development of cardiovascular diseases, including myocardial infarction. However, the underlying mechanisms are ill defined. Here we investigated the balance between prosurvival and detrimental pathways within the heart of C57Bl/6 male m...

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Detalles Bibliográficos
Autores principales: Mastrocola, Raffaella, Collino, Massimo, Penna, Claudia, Nigro, Debora, Chiazza, Fausto, Fracasso, Veronica, Tullio, Francesca, Alloatti, Giuseppe, Pagliaro, Pasquale, Aragno, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691622/
https://www.ncbi.nlm.nih.gov/pubmed/26788246
http://dx.doi.org/10.1155/2016/3480637