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The Role of PTEN in Myeloid Malignancies

PTEN deletion in the mouse and in the zebrafish highlights the essential role of this tumor suppressor in the development of myeloid malignancies, in particular acute myeloid leukemia and myeloproliferative disorders. In humans, extensive genetic sequences of myeloid malignancies did not reveal recu...

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Detalles Bibliográficos
Autores principales: Morotti, Alessandro, Panuzzo, Cristina, Crivellaro, Sabrina, Carrà, Giovanna, Torti, Davide, Guerrasio, Angelo, Saglio, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691678/
https://www.ncbi.nlm.nih.gov/pubmed/26734127
http://dx.doi.org/10.4081/hr.2015.6027