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Subcellular RNA profiling links splicing and nuclear DICER1 to alternative cleavage and polyadenylation

Alternative cleavage and polyadenylation (APA) plays a crucial role in the regulation of gene expression across eukaryotes. Although APA is extensively studied, its regulation within cellular compartments and its physiological impact remains largely enigmatic. Here, we used a rigorous subcellular fr...

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Detalles Bibliográficos
Autores principales: Neve, Jonathan, Burger, Kaspar, Li, Wencheng, Hoque, Mainul, Patel, Radhika, Tian, Bin, Gullerova, Monika, Furger, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691748/
https://www.ncbi.nlm.nih.gov/pubmed/26546131
http://dx.doi.org/10.1101/gr.193995.115