Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains

Recent advances enabled by the Hi-C technique have unraveled many principles of chromosomal folding that were subsequently linked to disease and gene regulation. In particular, Hi-C revealed that chromosomes of animals are organized into topologically associating domains (TADs), evolutionary conserv...

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Detalles Bibliográficos
Autores principales: Ulianov, Sergey V., Khrameeva, Ekaterina E., Gavrilov, Alexey A., Flyamer, Ilya M., Kos, Pavel, Mikhaleva, Elena A., Penin, Aleksey A., Logacheva, Maria D., Imakaev, Maxim V., Chertovich, Alexander, Gelfand, Mikhail S., Shevelyov, Yuri Y., Razin, Sergey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691752/
https://www.ncbi.nlm.nih.gov/pubmed/26518482
http://dx.doi.org/10.1101/gr.196006.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691752/
https://www.ncbi.nlm.nih.gov/pubmed/26518482
http://dx.doi.org/10.1101/gr.196006.115

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