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Novel regulation and functional interaction of polycistronic miRNAs

The importance of microRNAs in gene expression and disease is well recognized. However, what is less appreciated is that almost half of miRNA genes are organized in polycistronic clusters and are therefore coexpressed. The mir-11∼998 cluster consists of two miRNAs, miR-11 and miR-998. Here, we descr...

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Detalles Bibliográficos
Autores principales: Truscott, Mary, Islam, Abul B.M.M.K., Frolov, Maxim V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691827/
https://www.ncbi.nlm.nih.gov/pubmed/26554028
http://dx.doi.org/10.1261/rna.053264.115