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Structural basis for substrate recognition by the human N-terminal methyltransferase 1

α-N-terminal methylation represents a highly conserved and prevalent post-translational modification, yet its biological function has remained largely speculative. The recent discovery of α-N-terminal methyltransferase 1 (NTMT1) and its physiological substrates propels the elucidation of a general r...

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Detalles Bibliográficos
Autores principales: Dong, Cheng, Mao, Yunfei, Tempel, Wolfram, Qin, Su, Li, Li, Loppnau, Peter, Huang, Rong, Min, Jinrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691889/
https://www.ncbi.nlm.nih.gov/pubmed/26543161
http://dx.doi.org/10.1101/gad.270611.115