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Context-dependent modulation of Pol II CTD phosphatase SSUP-72 regulates alternative polyadenylation in neuronal development

Alternative polyadenylation (APA) is widespread in neuronal development and activity-mediated neural plasticity. However, the underlying molecular mechanisms are largely unknown. We used systematic genetic studies and genome-wide surveys of the transcriptional landscape to identify a context-depende...

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Detalles Bibliográficos
Autores principales: Chen, Fei, Zhou, Yu, Qi, Yingchuan B., Khivansara, Vishal, Li, Hairi, Chun, Sang Young, Kim, John K., Fu, Xiang-Dong, Jin, Yishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691892/
https://www.ncbi.nlm.nih.gov/pubmed/26588990
http://dx.doi.org/10.1101/gad.266650.115