SREBP and MDT-15 protect C. elegans from glucose-induced accelerated aging by preventing accumulation of saturated fat

Glucose-rich diets shorten the life spans of various organisms. However, the metabolic processes involved in this phenomenon remain unknown. Here, we show that sterol regulatory element-binding protein (SREBP) and mediator-15 (MDT-15) prevent the life-shortening effects of a glucose-rich diet by reg...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Dongyeop, Jeong, Dae-Eun, Son, Heehwa G., Yamaoka, Yasuyo, Kim, Hyunmin, Seo, Keunhee, Khan, Abdul Aziz, Roh, Tae-Young, Moon, Dae Won, Lee, Youngsook, Lee, Seung-Jae V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691952/
https://www.ncbi.nlm.nih.gov/pubmed/26637528
http://dx.doi.org/10.1101/gad.266304.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691952/
https://www.ncbi.nlm.nih.gov/pubmed/26637528
http://dx.doi.org/10.1101/gad.266304.115

Ejemplares similares