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Multi-Scale Genomic, Transcriptomic and Proteomic Analysis of Colorectal Cancer Cell Lines to Identify Novel Biomarkers

Selecting colorectal cancer (CRC) patients likely to respond to therapy remains a clinical challenge. The objectives of this study were to establish which genes were differentially expressed with respect to treatment sensitivity and relate this to copy number in a panel of 15 CRC cell lines. Copy nu...

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Detalles Bibliográficos
Autores principales: Briffa, Romina, Um, Inhwa, Faratian, Dana, Zhou, Ying, Turnbull, Arran K., Langdon, Simon P., Harrison, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692059/
https://www.ncbi.nlm.nih.gov/pubmed/26678268
http://dx.doi.org/10.1371/journal.pone.0144708