Cargando…

Multi-Scale Genomic, Transcriptomic and Proteomic Analysis of Colorectal Cancer Cell Lines to Identify Novel Biomarkers

Selecting colorectal cancer (CRC) patients likely to respond to therapy remains a clinical challenge. The objectives of this study were to establish which genes were differentially expressed with respect to treatment sensitivity and relate this to copy number in a panel of 15 CRC cell lines. Copy nu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Briffa, Romina, Um, Inhwa, Faratian, Dana, Zhou, Ying, Turnbull, Arran K., Langdon, Simon P., Harrison, David J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692059/ https://www.ncbi.nlm.nih.gov/pubmed/26678268 http://dx.doi.org/10.1371/journal.pone.0144708

Ejemplares similares

Sprouty 2 Is an Independent Prognostic Factor in Breast Cancer and May Be Useful in Stratifying Patients for Trastuzumab Therapy
por: Faratian, Dana, et al.
Publicado: (2011)

Heterogeneity Mapping of Protein Expression in Tumors using Quantitative Immunofluorescence
por: Faratian, Dana, et al.
Publicado: (2011)

The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer
por: Huang, Rui, et al.
Publicado: (2015)

Novel Monte Carlo approach quantifies data assemblage utility and reveals power of integrating molecular and clinical information for cancer prognosis
por: Verleyen, Wim, et al.
Publicado: (2015)

GnRH receptor activation competes at a low level with growth signaling in stably transfected human breast cell lines
por: Morgan, Kevin, et al.
Publicado: (2011)

Transcript and protein profiling identifies signaling, growth arrest, apoptosis, and NF-κB survival signatures following GNRH receptor activation
por: Meyer, Colette, et al.
Publicado: (2013)

A comparative analysis of inhibitors of the glycolysis pathway in breast and ovarian cancer cell line models
por: Xintaropoulou, Chrysi, et al.
Publicado: (2015)

Novel histopathologic feature identified through image analysis augments stage II colorectal cancer clinical reporting
por: Caie, Peter D., et al.
Publicado: (2016)

Model-based global sensitivity analysis as applied to identification of anti-cancer drug targets and biomarkers of drug resistance in the ErbB2/3 network
por: Lebedeva, Galina, et al.
Publicado: (2012)

Increased STAT1 Signaling in Endocrine-Resistant Breast Cancer
por: Huang, Rui, et al.
Publicado: (2014)

Dynamic modulation of phosphoprotein expression in ovarian cancer xenograft models
por: Koussounadis, Antonis, et al.
Publicado: (2016)

Systems pathology
por: Faratian, Dana
Publicado: (2010)

Predictive markers of endocrine response in breast cancer
por: Mosly, Duniya, et al.
Publicado: (2018)

Defining the molecular response to trastuzumab, pertuzumab and combination therapy in ovarian cancer
por: Sims, A H, et al.
Publicado: (2012)

Quantification of tumour budding, lymphatic vessel density and invasion through image analysis in colorectal cancer
por: Caie, Peter D, et al.
Publicado: (2014)

Development and characterisation of acquired radioresistant breast cancer cell lines
por: Gray, Mark, et al.
Publicado: (2019)

Differential Integration of Transcriptome and Proteome Identifies Pan-Cancer Prognostic Biomarkers
por: Schwartz, Gregory W., et al.
Publicado: (2018)

Proteome and transcriptome analyses of wheat near isogenic lines identifies key proteins and genes of wheat bread quality
por: Lv, Liangjie, et al.
Publicado: (2021)

Dynamic changes in gene expression in vivo predict prognosis of tamoxifen-treated patients with breast cancer
por: Taylor, Karen J, et al.
Publicado: (2010)

Identifying causal genes for migraine by integrating the proteome and transcriptome
por: Li, Shuang-jie, et al.
Publicado: (2023)

Transcriptomic and Proteomic Analyses of Celery Cytoplasmic Male Sterile Line and Its Maintainer Line
por: Wang, Haoran, et al.
Publicado: (2023)

Expression of steroid receptor coactivator 3 in ovarian epithelial cancer is a poor prognostic factor and a marker for platinum resistance
por: Palmieri, C, et al.
Publicado: (2013)

Deep Phospho- and Phosphotyrosine Proteomics Identified Active Kinases and Phosphorylation Networks in Colorectal Cancer Cell Lines Resistant to Cetuximab
por: Abe, Yuichi, et al.
Publicado: (2017)

Identifier mapping performance for integrating transcriptomics and proteomics experimental results
por: Day, Roger S, et al.
Publicado: (2011)

Key Genes Identified in Nonsyndromic Microtia by the Analysis of Transcriptomics and Proteomics
por: Chen, Xin, et al.
Publicado: (2022)

Identifying the genes impacted by cell proliferation in proteomics and transcriptomics studies
por: Locard-Paulet, Marie, et al.
Publicado: (2022)

Deep proteome and transcriptome mapping of a human cancer cell line
por: Nagaraj, Nagarjuna, et al.
Publicado: (2011)

Defining the transcriptome and proteome in three functionally different human cell lines
por: Lundberg, Emma, et al.
Publicado: (2010)

Characterization of Metronidazole-Resistant Giardia intestinalis Lines by Comparative Transcriptomics and Proteomics
por: Krakovka, Sascha, et al.
Publicado: (2022)

Integrating proteomics and transcriptomics for the identification of potential targets in early colorectal cancer
por: Yang, Wang, et al.
Publicado: (2019)

Prospective Proteomic Study Identifies Potential Circulating Protein Biomarkers for Colorectal Cancer Risk
por: Sun, Xiaohui, et al.
Publicado: (2022)

C35 overexpression defines subsets of human breast cancer and its immunoreceptor tyrosine-based activation motif represents a novel treatment target
por: Katz, E, et al.
Publicado: (2008)

An Integrative Transcriptomics and Proteomics Approach to Identify Putative Genes Underlying Fruit Ripening in Tomato near Isogenic Lines with Long Shelf Life
por: Di Giacomo, Melisa, et al.
Publicado: (2023)

Integrated transcriptomic and proteomic analysis of a cytoplasmic male sterility line and associated maintainer line in soybean
por: Wang, Dagang, et al.
Publicado: (2023)

Integrated Genomic, Transcriptomic and Proteomic Analysis for Identifying Markers of Alzheimer’s Disease
por: Madrid, Laura, et al.
Publicado: (2021)

Cerebellar axonopathy in Shivers horses identified by spatial transcriptomic and proteomic analyses
por: Valberg, Stephanie J., et al.
Publicado: (2023)

A multi-omics dataset of human transcriptome and proteome stable reference
por: Lu, Shaohua, et al.
Publicado: (2023)

Comprehensive analysis of the genome transcriptome and proteome landscapes of three tumor cell lines
por: Akan, Pelin, et al.
Publicado: (2012)

Comparative Transcriptomics and Proteomics of Cancer Cell Lines Cultivated by Physiological and Commercial Media
por: Wang, Junyao, et al.
Publicado: (2022)

Proteomic Characterization of Colorectal Cancer Tissue from Patients Identifies Novel Putative Protein Biomarkers
por: Ludvigsen, Maja, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_cng6kdj8vjq67ecg5grsd28je9