Selective Loss of Early Differentiated, Highly Functional PD1(high) CD4 T Cells with HIV Progression

The role of PD-1 expression on CD4 T cells during HIV infection is not well understood. Here, we describe the differential expression of PD-1 in CD127(high) CD4 T cells within the early/intermediate differentiated (EI) (CD27(high)CD45RA(low)) T cell population among uninfected and HIV-infected subje...

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Detalles Bibliográficos
Autores principales: Paris, Robert M., Petrovas, Constantinos, Ferrando-Martinez, Sara, Moysi, Eirini, Boswell, Kristin L., Archer, Eva, Yamamoto, Takuya, Ambrozak, David, Casazza, Joseph P., Haubrich, Richard, Connors, Mark, Ake, Julie, Kim, Jerome H., Koup, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692060/
https://www.ncbi.nlm.nih.gov/pubmed/26678998
http://dx.doi.org/10.1371/journal.pone.0144767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692060/
https://www.ncbi.nlm.nih.gov/pubmed/26678998
http://dx.doi.org/10.1371/journal.pone.0144767

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