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N-terminal modifications of cellular proteins: The enzymes involved, their substrate specificities and biological effects

The vast majority of eukaryotic proteins are N-terminally modified by one or more processing enzymes. Enzymes acting on the very first amino acid of a polypeptide include different peptidases, transferases, and ligases. Methionine aminopeptidases excise the initiator methionine leaving the nascent p...

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Detalles Bibliográficos
Autores principales: Varland, Sylvia, Osberg, Camilla, Arnesen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692089/
https://www.ncbi.nlm.nih.gov/pubmed/25914051
http://dx.doi.org/10.1002/pmic.201400619