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Microphthalmia‐associated transcription factor in melanoma development and MAP‐kinase pathway targeted therapy

Malignant melanoma is a neoplasm of melanocytes, and the microphthalmia‐associated transcription factor (MITF) is essential for the existence of melanocytes. MITF's relevance for this cell lineage is maintained in melanoma, where it is an important regulator of survival and balances melanoma ce...

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Detalles Bibliográficos
Autores principales: Wellbrock, Claudia, Arozarena, Imanol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692100/
https://www.ncbi.nlm.nih.gov/pubmed/25818589
http://dx.doi.org/10.1111/pcmr.12370