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Downregulation of the Canonical WNT Signaling Pathway by TGFβ1 Inhibits Photoreceptor Differentiation of Adult Human Müller Glia with Stem Cell Characteristics
Müller glia are responsible for the retina regeneration observed in zebrafish. Although the human retina harbors Müller glia with stem cell characteristics, there is no evidence that they regenerate the retina after disease or injury. Transforming growth factor-β (TGFβ) and Wnt signaling regulate re...
Autores principales: | Angbohang, Angshumonik, Wu, Na, Charalambous, Thalis, Eastlake, Karen, Lei, Yuan, Kim, Yung Su, Sun, Xinghuai H., Limb, G. Astrid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692127/ https://www.ncbi.nlm.nih.gov/pubmed/26456050 http://dx.doi.org/10.1089/scd.2015.0262 |
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