Downregulation of the Canonical WNT Signaling Pathway by TGFβ1 Inhibits Photoreceptor Differentiation of Adult Human Müller Glia with Stem Cell Characteristics

Müller glia are responsible for the retina regeneration observed in zebrafish. Although the human retina harbors Müller glia with stem cell characteristics, there is no evidence that they regenerate the retina after disease or injury. Transforming growth factor-β (TGFβ) and Wnt signaling regulate re...

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Detalles Bibliográficos
Autores principales: Angbohang, Angshumonik, Wu, Na, Charalambous, Thalis, Eastlake, Karen, Lei, Yuan, Kim, Yung Su, Sun, Xinghuai H., Limb, G. Astrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Original Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692127/
https://www.ncbi.nlm.nih.gov/pubmed/26456050
http://dx.doi.org/10.1089/scd.2015.0262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692127/
https://www.ncbi.nlm.nih.gov/pubmed/26456050
http://dx.doi.org/10.1089/scd.2015.0262

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