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Sources of Variability in a Synthetic Gene Oscillator

Synthetic gene oscillators are small, engineered genetic circuits that produce periodic variations in target protein expression. Like other gene circuits, synthetic gene oscillators are noisy and exhibit fluctuations in amplitude and period. Understanding the origins of such variability is key to bu...

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Detalles Bibliográficos
Autores principales: Veliz-Cuba, Alan, Hirning, Andrew J., Atanas, Adam A., Hussain, Faiza, Vancia, Flavia, Josić, Krešimir, Bennett, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692282/
https://www.ncbi.nlm.nih.gov/pubmed/26693906
http://dx.doi.org/10.1371/journal.pcbi.1004674