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Determination of Protein-ligand Interactions Using Differential Scanning Fluorimetry

A wide range of methods are currently available for determining the dissociation constant between a protein and interacting small molecules. However, most of these require access to specialist equipment, and often require a degree of expertise to effectively establish reliable experiments and analyz...

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Detalles Bibliográficos
Autores principales: Vivoli, Mirella, Novak, Halina R., Littlechild, Jennifer A., Harmer, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692391/
https://www.ncbi.nlm.nih.gov/pubmed/25285605
http://dx.doi.org/10.3791/51809