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Patients with Dilated Cardiomyopathy and Sustained Monomorphic Ventricular Tachycardia Show Up-Regulation of KCNN3 and KCNJ2 Genes and CACNG8-Linked Left Ventricular Dysfunction

AIMS: Disruptions in cardiac ion channels have shown to influence the impaired cardiac contraction in heart failure. We sought to determine the altered gene expression profile of this category in dilated cardiomyopathy (DCM) patients and relate the altered gene expression with the clinical signs pre...

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Detalles Bibliográficos
Autores principales: Ortega, Ana, Tarazón, Estefanía, Roselló-Lletí, Esther, Gil-Cayuela, Carolina, Lago, Francisca, González-Juanatey, Jose-Ramón, Cinca, Juan, Jorge, Esther, Martínez-Dolz, Luis, Portolés, Manuel, Rivera, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692400/
https://www.ncbi.nlm.nih.gov/pubmed/26710323
http://dx.doi.org/10.1371/journal.pone.0145518