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TM4SF1 Promotes Gemcitabine Resistance of Pancreatic Cancer In Vitro and In Vivo

BACKGROUND: TM4SF1 is overexpressed in pancreatic ductal adenocarcinoma (PDAC) and affects the development of this cancer. Also, multidrug resistance (MDR) is generally associated with tumor chemoresistance in pancreatic cancer. However, the correlation between TM4SF1 and MDR remains unknown. This r...

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Detalles Bibliográficos
Autores principales: Cao, Jia, Yang, Jiachun, Ramachandran, Vijaya, Arumugam, Thiruvengadam, Deng, Defeng, Li, Zhaoshen, Xu, Leiming, Logsdon, Craig D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692438/
https://www.ncbi.nlm.nih.gov/pubmed/26709920
http://dx.doi.org/10.1371/journal.pone.0144969