Cargando…
Type I Interferon Induced Epigenetic Regulation of Macrophages Suppresses Innate and Adaptive Immunity in Acute Respiratory Viral Infection
Influenza A virus (IAV) is an airborne pathogen that causes significant morbidity and mortality each year. Macrophages (Mϕ) are the first immune population to encounter IAV virions in the lungs and are required to control infection. In the present study, we explored the mechanism by which cytokine s...
Autores principales: | Kroetz, Danielle N., Allen, Ronald M., Schaller, Matthew A., Cavallaro, Cleyton, Ito, Toshihiro, Kunkel, Steven L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692439/ https://www.ncbi.nlm.nih.gov/pubmed/26709698 http://dx.doi.org/10.1371/journal.ppat.1005338 |
Ejemplares similares
-
The linkage of innate and adaptive immune response during granulomatous development
por: Ito, Toshihiro, et al.
Publicado: (2013) -
Respiratory viral infections drive chemokine expression and exacerbate the asthmatic response
por: Schaller, Matthew, et al.
Publicado: (2006) -
The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections
por: Egli, Adrian, et al.
Publicado: (2014) -
Cytokine Induced Phenotypic and Epigenetic Signatures Are Key to Establishing Specific Macrophage Phenotypes
por: Kittan, Nicolai A., et al.
Publicado: (2013) -
Viral suppression of the interferon system
por: Weber, Friedemann, et al.
Publicado: (2007)