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Application of neurite orientation dispersion and density imaging (NODDI) to a tau pathology model of Alzheimer's disease

Increased hyperphosphorylated tau and the formation of intracellular neurofibrillary tangles are associated with the loss of neurons and cognitive decline in Alzheimer's disease, and related neurodegenerative conditions. We applied two diffusion models, diffusion tensor imaging (DTI) and neurit...

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Detalles Bibliográficos
Autores principales: Colgan, N., Siow, B., O'Callaghan, J.M., Harrison, I.F., Wells, J.A., Holmes, H.E., Ismail, O., Richardson, S., Alexander, D.C., Collins, E.C., Fisher, E.M., Johnson, R., Schwarz, A.J., Ahmed, Z., O'Neill, M.J., Murray, T.K., Zhang, H., Lythgoe, M.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692518/
https://www.ncbi.nlm.nih.gov/pubmed/26505297
http://dx.doi.org/10.1016/j.neuroimage.2015.10.043