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Application of neurite orientation dispersion and density imaging (NODDI) to a tau pathology model of Alzheimer's disease
Increased hyperphosphorylated tau and the formation of intracellular neurofibrillary tangles are associated with the loss of neurons and cognitive decline in Alzheimer's disease, and related neurodegenerative conditions. We applied two diffusion models, diffusion tensor imaging (DTI) and neurit...
Autores principales: | Colgan, N., Siow, B., O'Callaghan, J.M., Harrison, I.F., Wells, J.A., Holmes, H.E., Ismail, O., Richardson, S., Alexander, D.C., Collins, E.C., Fisher, E.M., Johnson, R., Schwarz, A.J., Ahmed, Z., O'Neill, M.J., Murray, T.K., Zhang, H., Lythgoe, M.F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692518/ https://www.ncbi.nlm.nih.gov/pubmed/26505297 http://dx.doi.org/10.1016/j.neuroimage.2015.10.043 |
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