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Estimation of Inhibitory Effect against Tyrosinase Activity through Homology Modeling and Molecular Docking

Tyrosinase is a key enzyme in melanogenesis. Generally, mushroom tyrosinase from A. bisporus had been used as a model in skin-whitening agent tests employed in the cosmetic industry. The recently obtained crystal structure of bacterial tyrosinase from B. megaterium has high similarity (33.5%) to the...

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Detalles Bibliográficos
Autores principales: Nokinsee, Daungkamon, Shank, Lalida, Lee, Vannajan Sanghiran, Nimmanpipug, Piyarat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693013/
https://www.ncbi.nlm.nih.gov/pubmed/26788364
http://dx.doi.org/10.1155/2015/262364