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Dasatinib and Doxorubicin Treatment of Sarcoma Initiating Cells: A Possible New Treatment Strategy

Background. One of the major challenges affecting sarcoma treatment outcome, particularly that of metastatic disease, is resistance to chemotherapy. Cancer-initiating cells are considered a major contributor to this resistance. Methods. An immortalised nontransformed human stromal (mesenchymal) stem...

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Detalles Bibliográficos
Autores principales: Aggerholm-Pedersen, Ninna, Demuth, Christina, Safwat, Akmal, Meldgaard, Peter, Kassem, Moustapha, Sandahl Sorensen, Boe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693025/
https://www.ncbi.nlm.nih.gov/pubmed/26788073
http://dx.doi.org/10.1155/2016/9601493