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Absence of Rybp Compromises Neural Differentiation of Embryonic Stem Cells

Rybp (Ring1 and Yy1 Binding Protein) is a transcriptional regulator and member of the noncanonical polycomb repressive complex 1 with essential role in early embryonic development. We have previously described that alteration of Rybp dosage in mouse models induced striking neural tube defects (NTDs)...

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Detalles Bibliográficos
Autores principales: Kovacs, Gergo, Szabo, Viktoria, Pirity, Melinda K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693026/
https://www.ncbi.nlm.nih.gov/pubmed/26788067
http://dx.doi.org/10.1155/2016/4034620