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Absence of Rybp Compromises Neural Differentiation of Embryonic Stem Cells
Rybp (Ring1 and Yy1 Binding Protein) is a transcriptional regulator and member of the noncanonical polycomb repressive complex 1 with essential role in early embryonic development. We have previously described that alteration of Rybp dosage in mouse models induced striking neural tube defects (NTDs)...
Autores principales: | Kovacs, Gergo, Szabo, Viktoria, Pirity, Melinda K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693026/ https://www.ncbi.nlm.nih.gov/pubmed/26788067 http://dx.doi.org/10.1155/2016/4034620 |
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