Differential Contributions of the Complement Anaphylotoxin Receptors C5aR1 and C5aR2 to the Early Innate Immune Response against Staphylococcus aureus Infection

The complement anaphylatoxin C5a contributes to host defense against Staphylococcus aureus. In this study, we investigated the functional role of the two known C5a receptors, C5aR1 and C5aR2, in the host response to S. aureus. We found that C5aR1(−/−) mice exhibited greater susceptibility to S. aure...

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Detalles Bibliográficos
Autores principales: Horst, Sarah A., Itzek, Andreas, Klos, Andreas, Beineke, Andreas, Medina, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693161/
https://www.ncbi.nlm.nih.gov/pubmed/26512700
http://dx.doi.org/10.3390/pathogens4040722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693161/
https://www.ncbi.nlm.nih.gov/pubmed/26512700
http://dx.doi.org/10.3390/pathogens4040722

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