Cargando…

Arsenic Disruption of DNA Damage Responses—Potential Role in Carcinogenesis and Chemotherapy

Arsenic is a Class I human carcinogen and is widespread in the environment. Chronic arsenic exposure causes cancer in skin, lung and bladder, as well as in other organs. Paradoxically, arsenic also is a potent chemotherapeutic against acute promyelocytic leukemia and can potentiate the cytotoxic eff...

Descripción completa

Detalles Bibliográficos
Autores principales: Muenyi, Clarisse S., Ljungman, Mats, States, J. Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693233/
https://www.ncbi.nlm.nih.gov/pubmed/26404387
http://dx.doi.org/10.3390/biom5042184