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Arsenic Disruption of DNA Damage Responses—Potential Role in Carcinogenesis and Chemotherapy
Arsenic is a Class I human carcinogen and is widespread in the environment. Chronic arsenic exposure causes cancer in skin, lung and bladder, as well as in other organs. Paradoxically, arsenic also is a potent chemotherapeutic against acute promyelocytic leukemia and can potentiate the cytotoxic eff...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693233/ https://www.ncbi.nlm.nih.gov/pubmed/26404387 http://dx.doi.org/10.3390/biom5042184 |