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New Insights into the Biological Role of Mammalian ADARs; the RNA Editing Proteins

The ADAR proteins deaminate adenosine to inosine in double-stranded RNA which is one of the most abundant modifications present in mammalian RNA. Inosine can have a profound effect on the RNAs that are edited, not only changing the base-pairing properties, but can also result in recoding, as inosine...

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Detalles Bibliográficos
Autores principales: Mannion, Niamh, Arieti, Fabiana, Gallo, Angela, Keegan, Liam P., O’Connell, Mary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693238/
https://www.ncbi.nlm.nih.gov/pubmed/26437436
http://dx.doi.org/10.3390/biom5042338