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The Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and Repair

The maintenance of genomic integrity is an important process in organisms as failure to sense and repair damaged DNA can result in a variety of diseases. Eukaryotic cells have developed complex DNA repair response (DDR) mechanisms to accurately sense and repair damaged DNA. Post-translational modifi...

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Detalles Bibliográficos
Autores principales: Chung, Dudley, Dellaire, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693240/
https://www.ncbi.nlm.nih.gov/pubmed/26437438
http://dx.doi.org/10.3390/biom5042388