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The Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and Repair
The maintenance of genomic integrity is an important process in organisms as failure to sense and repair damaged DNA can result in a variety of diseases. Eukaryotic cells have developed complex DNA repair response (DDR) mechanisms to accurately sense and repair damaged DNA. Post-translational modifi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693240/ https://www.ncbi.nlm.nih.gov/pubmed/26437438 http://dx.doi.org/10.3390/biom5042388 |