Cargando…
The Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and Repair
The maintenance of genomic integrity is an important process in organisms as failure to sense and repair damaged DNA can result in a variety of diseases. Eukaryotic cells have developed complex DNA repair response (DDR) mechanisms to accurately sense and repair damaged DNA. Post-translational modifi...
Autores principales: | Chung, Dudley, Dellaire, Graham |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693240/ https://www.ncbi.nlm.nih.gov/pubmed/26437438 http://dx.doi.org/10.3390/biom5042388 |
Ejemplares similares
-
The Cellular and Developmental Roles of Cullins, Neddylation, and the COP9 Signalosome in Dictyostelium discoideum
por: Kim, William D., et al.
Publicado: (2022) -
COP9-Signalosome deneddylase activity is enhanced by simultaneous neddylation: insights into the regulation of an enzymatic protein complex
por: Bornstein, Gil, et al.
Publicado: (2015) -
Role of the COP9 Signalosome (CSN) in Cardiovascular Diseases
por: Milic, Jelena, et al.
Publicado: (2019) -
Epidermal Growth Factor Receptor neddylation is regulated by a desmosomal-COP9 (Constitutive Photomorphogenesis 9) signalosome complex
por: Najor, Nicole Ann, et al.
Publicado: (2017) -
Targeting the COP9 signalosome for cancer therapy
por: Du, Wenqi, et al.
Publicado: (2022)