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Αlpha-Synuclein as a Mediator in the Interplay between Aging and Parkinson’s Disease

Accumulation and misfolding of the alpha-synuclein protein are core mechanisms in the pathogenesis of Parkinson’s disease. While the normal function of alpha-synuclein is mainly related to the control of vesicular neurotransmission, its pathogenic effects are linked to various cellular functions, wh...

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Detalles Bibliográficos
Autores principales: Bobela, Wojciech, Aebischer, Patrick, Schneider, Bernard Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693253/
https://www.ncbi.nlm.nih.gov/pubmed/26501339
http://dx.doi.org/10.3390/biom5042675