Novel Implications of DNA Damage Response in Drug Resistance of Malignant Cancers Obtained from the Functional Interaction between p53 Family and RUNX2

During the lifespan of cells, their genomic DNA is continuously exposed to the endogenous and exogenous DNA insults. Thus, the appropriate cellular response to DNA damage plays a pivotal role in maintaining genomic integrity and also acts as a molecular barrier towards DNA legion-mediated carcinogen...

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Detalles Bibliográficos
Autores principales: Ozaki, Toshinori, Nakamura, Mizuyo, Shimozato, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693260/
https://www.ncbi.nlm.nih.gov/pubmed/26512706
http://dx.doi.org/10.3390/biom5042854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693260/
https://www.ncbi.nlm.nih.gov/pubmed/26512706
http://dx.doi.org/10.3390/biom5042854

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