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ATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to Adaptor

The recognition, signalling and repair of DNA double strand breaks (DSB) involves the participation of a multitude of proteins and post-translational events that ensure maintenance of genome integrity. Amongst the proteins involved are several which when mutated give rise to genetic disorders charac...

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Detalles Bibliográficos
Autores principales: Lavin, Martin F., Kozlov, Sergei, Gatei, Magtouf, Kijas, Amanda W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693261/
https://www.ncbi.nlm.nih.gov/pubmed/26512707
http://dx.doi.org/10.3390/biom5042877