RNase P-Mediated Sequence-Specific Cleavage of RNA by Engineered External Guide Sequences

The RNA cleavage activity of RNase P can be employed to decrease the levels of specific RNAs and to study their function or even to eradicate pathogens. Two different technologies have been developed to use RNase P as a tool for RNA knockdown. In one of these, an external guide sequence, which mimic...

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Detalles Bibliográficos
Autores principales: Derksen, Merel, Mertens, Vicky, Pruijn, Ger J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693268/
https://www.ncbi.nlm.nih.gov/pubmed/26569326
http://dx.doi.org/10.3390/biom5043029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693268/
https://www.ncbi.nlm.nih.gov/pubmed/26569326
http://dx.doi.org/10.3390/biom5043029

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