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RNase P-Mediated Sequence-Specific Cleavage of RNA by Engineered External Guide Sequences
The RNA cleavage activity of RNase P can be employed to decrease the levels of specific RNAs and to study their function or even to eradicate pathogens. Two different technologies have been developed to use RNase P as a tool for RNA knockdown. In one of these, an external guide sequence, which mimic...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693268/ https://www.ncbi.nlm.nih.gov/pubmed/26569326 http://dx.doi.org/10.3390/biom5043029 |