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Buserelin treatment to rats causes enteric neurodegeneration with moderate effects on CRF-immunoreactive neurons and Enterobacteriaceae in colon, and in acetylcholine-mediated permeability in ileum

BACKGROUND: The gonadotropin-releasing hormone (GnRH) analog buserelin causes enteric neuronal loss. Acute stress or injection of corticotropin-releasing factor (CRF) affects motility, secretion, and barrier function of the gastrointestinal tract. The aim of the study was to characterize the CRF imm...

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Detalles Bibliográficos
Autores principales: Sand, Elin, Linninge, Caroline, Lozinska, Liudmyla, Egecioglu, Emil, Roth, Bodil, Molin, Göran, Weström, Björn, Ekblad, Eva, Ohlsson, Bodil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693429/
https://www.ncbi.nlm.nih.gov/pubmed/26710832
http://dx.doi.org/10.1186/s13104-015-1800-x