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Buserelin treatment to rats causes enteric neurodegeneration with moderate effects on CRF-immunoreactive neurons and Enterobacteriaceae in colon, and in acetylcholine-mediated permeability in ileum
BACKGROUND: The gonadotropin-releasing hormone (GnRH) analog buserelin causes enteric neuronal loss. Acute stress or injection of corticotropin-releasing factor (CRF) affects motility, secretion, and barrier function of the gastrointestinal tract. The aim of the study was to characterize the CRF imm...
Autores principales: | Sand, Elin, Linninge, Caroline, Lozinska, Liudmyla, Egecioglu, Emil, Roth, Bodil, Molin, Göran, Weström, Björn, Ekblad, Eva, Ohlsson, Bodil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693429/ https://www.ncbi.nlm.nih.gov/pubmed/26710832 http://dx.doi.org/10.1186/s13104-015-1800-x |
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