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CBX7 and miR‐9 are part of an autoregulatory loop controlling p16(INK) (4a)

Polycomb repressive complexes (PRC1 and PRC2) are epigenetic regulators that act in coordination to influence multiple cellular processes including pluripotency, differentiation, cancer and senescence. The role of PRCs in senescence can be mostly explained by their ability to repress the INK4/ARF lo...

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Detalles Bibliográficos
Autores principales: O'Loghlen, Ana, Brookes, Sharon, Martin, Nadine, Rapisarda, Valentina, Peters, Gordon, Gil, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693451/
https://www.ncbi.nlm.nih.gov/pubmed/26416703
http://dx.doi.org/10.1111/acel.12404