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Altering sphingolipid composition with aging induces contractile dysfunction of gastric smooth muscle via K(C) (a)1.1 upregulation
K(C) (a)1.1 regulates smooth muscle contractility by modulating membrane potential, and age‐associated changes in K(C) (a)1.1 expression may contribute to the development of motility disorders of the gastrointestinal tract. Sphingolipids (SLs) are important structural components of cellular membrane...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693452/ https://www.ncbi.nlm.nih.gov/pubmed/26288989 http://dx.doi.org/10.1111/acel.12388 |