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Altering sphingolipid composition with aging induces contractile dysfunction of gastric smooth muscle via K(C) (a)1.1 upregulation

K(C) (a)1.1 regulates smooth muscle contractility by modulating membrane potential, and age‐associated changes in K(C) (a)1.1 expression may contribute to the development of motility disorders of the gastrointestinal tract. Sphingolipids (SLs) are important structural components of cellular membrane...

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Detalles Bibliográficos
Autores principales: Choi, Shinkyu, Kim, Ji Aee, Kim, Tae Hun, Li, Hai‐yan, Shin, Kyong‐Oh, Lee, Yong‐Moon, Oh, Seikwan, Pewzner‐Jung, Yael, Futerman, Anthony H., Suh, Suk Hyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693452/
https://www.ncbi.nlm.nih.gov/pubmed/26288989
http://dx.doi.org/10.1111/acel.12388