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Atypical antidepressants extend lifespan of Caenorhabditis elegans by activation of a non‐cell‐autonomous stress response

Oxidative stress has long been associated with aging and has recently been linked to psychiatric disorders, including psychosis and depression. We identified multiple antipsychotics and antidepressants that extend Caenorhabditis elegans lifespan and protect the animal from oxidative stress. Here, we...

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Detalles Bibliográficos
Autores principales: Rangaraju, Sunitha, Solis, Gregory M., Andersson, Sofia I., Gomez‐Amaro, Rafael L., Kardakaris, Rozina, Broaddus, Caroline D., Niculescu, Alexander B., Petrascheck, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693466/
https://www.ncbi.nlm.nih.gov/pubmed/26255886
http://dx.doi.org/10.1111/acel.12379