The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging

Sarcopenia, the loss of skeletal muscle mass and function during aging, is a major contributor to disability and frailty in the elderly. Previous studies found a protective effect of reduced histone deacetylase activity in models of neurogenic muscle atrophy. Because loss of muscle mass during aging...

Descripción completa

Detalles Bibliográficos
Autores principales: Walsh, Michael E., Bhattacharya, Arunabh, Sataranatarajan, Kavithalakshmi, Qaisar, Rizwan, Sloane, Lauren, Rahman, Md M., Kinter, Michael, Van Remmen, Holly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693467/
https://www.ncbi.nlm.nih.gov/pubmed/26290460
http://dx.doi.org/10.1111/acel.12387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693467/
https://www.ncbi.nlm.nih.gov/pubmed/26290460
http://dx.doi.org/10.1111/acel.12387

Ejemplares similares