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Infection susceptibility and immune senescence with advancing age replicated in accelerated aging Lmna (Dhe) mice
Aging confers increased susceptibility to common pathogens including influenza A virus. Despite shared vulnerability to infection with advancing age in humans and rodents, the relatively long time required for immune senescence to take hold practically restricts the use of naturally aged mice to inv...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693468/ https://www.ncbi.nlm.nih.gov/pubmed/26248606 http://dx.doi.org/10.1111/acel.12385 |