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Infection susceptibility and immune senescence with advancing age replicated in accelerated aging Lmna (Dhe) mice

Aging confers increased susceptibility to common pathogens including influenza A virus. Despite shared vulnerability to infection with advancing age in humans and rodents, the relatively long time required for immune senescence to take hold practically restricts the use of naturally aged mice to inv...

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Detalles Bibliográficos
Autores principales: Xin, Lijun, Jiang, Tony T., Kinder, Jeremy M., Ertelt, James M., Way, Sing Sing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693468/
https://www.ncbi.nlm.nih.gov/pubmed/26248606
http://dx.doi.org/10.1111/acel.12385