CYP‐mediated drug–drug interactions with evacetrapib, an investigational CETP inhibitor: in vitro prediction and clinical outcome

AIMS: Evacetrapib is a cholesteryl ester transfer protein (CETP) inhibitor under development for reducing cardiovascular events in patients with high risk vascular disease. CETP inhibitors are likely to be utilized as ‘add‐on’ therapy to statins in patients receiving concomitant medications, so the...

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Detalles Bibliográficos
Autores principales: Cannady, Ellen A., Suico, Jeffrey G., Wang, Ming‐Dauh, Friedrich, Stuart, Rehmel, Jessica R. F., Nicholls, Stephen J., Krueger, Kathryn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Drug Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693478/
https://www.ncbi.nlm.nih.gov/pubmed/26264702
http://dx.doi.org/10.1111/bcp.12730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693478/
https://www.ncbi.nlm.nih.gov/pubmed/26264702
http://dx.doi.org/10.1111/bcp.12730

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