Cholesterol‐loaded nanoparticles ameliorate synaptic and cognitive function in Huntington's disease mice

Brain cholesterol biosynthesis and cholesterol levels are reduced in mouse models of Huntington's disease (HD), suggesting that locally synthesized, newly formed cholesterol is less available to neurons. This may be detrimental for neuronal function, especially given that locally synthesized ch...

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Detalles Bibliográficos
Autores principales: Valenza, Marta, Chen, Jane Y, Di Paolo, Eleonora, Ruozi, Barbara, Belletti, Daniela, Ferrari Bardile, Costanza, Leoni, Valerio, Caccia, Claudio, Brilli, Elisa, Di Donato, Stefano, Boido, Marina M, Vercelli, Alessandro, Vandelli, Maria A, Forni, Flavio, Cepeda, Carlos, Levine, Michael S, Tosi, Giovanni, Cattaneo, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693506/
https://www.ncbi.nlm.nih.gov/pubmed/26589247
http://dx.doi.org/10.15252/emmm.201505413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693506/
https://www.ncbi.nlm.nih.gov/pubmed/26589247
http://dx.doi.org/10.15252/emmm.201505413

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