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Hypomyelination following deletion of Tsc2 in oligodendrocyte precursors

OBJECTIVE: While abnormalities in myelin in tuberous sclerosis complex (TSC) have been known for some time, recent imaging‐based data suggest myelin abnormalities may be independent of the pathognomonic cortical lesions (“tubers”). Multiple mouse models of TSC exhibit myelination deficits, though th...

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Detalles Bibliográficos
Autores principales: Carson, Robert P., Kelm, Nathaniel D., West, Kathryn L., Does, Mark D., Fu, Cary, Weaver, Grace, McBrier, Eleanor, Parker, Brittany, Grier, Mark D., Ess, Kevin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693589/
https://www.ncbi.nlm.nih.gov/pubmed/26734657
http://dx.doi.org/10.1002/acn3.254