Chronic enzyme replacement therapy ameliorates neuropathology in alpha‐mannosidosis mice

OBJECTIVE: The lysosomal storage disease alpha‐mannosidosis is caused by the deficiency of the lysosomal acid hydrolase alpha‐mannosidase (LAMAN) leading to lysosomal accumulation of neutral mannose‐linked oligosaccharides throughout the body, including the brain. Clinical findings in alpha‐mannosid...

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Detalles Bibliográficos
Autores principales: Damme, Markus, Stroobants, Stijn, Lüdemann, Meike, Rothaug, Michelle, Lüllmann‐Rauch, Renate, Beck, Hans Christian, Ericsson, Annika, Andersson, Claes, Fogh, Jens, D'Hooge, Rudi, Saftig, Paul, Blanz, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693626/
https://www.ncbi.nlm.nih.gov/pubmed/26817023
http://dx.doi.org/10.1002/acn3.245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693626/
https://www.ncbi.nlm.nih.gov/pubmed/26817023
http://dx.doi.org/10.1002/acn3.245

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