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Identification of potential glucocorticoid receptor therapeutic targets in multiple myeloma

Glucocorticoids (GC) are a cornerstone of combination therapies for multiple myeloma. However, patients ultimately develop resistance to GCs frequently based on decreased glucocorticoid receptor (GR) expression. An understanding of the direct targets of GC actions, which induce cell death, is expect...

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Detalles Bibliográficos
Autores principales: Thomas, Alexandra L., Coarfa, Cristian, Qian, Jun, Wilkerson, Joseph J., Rajapakshe, Kimal, Krett, Nancy L., Gunaratne, Preethi H., Rosen, Steven T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nuclear Receptor Signaling Atlas 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693629/
https://www.ncbi.nlm.nih.gov/pubmed/26715915
http://dx.doi.org/10.1621/nrs.13006