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Identification of potential glucocorticoid receptor therapeutic targets in multiple myeloma
Glucocorticoids (GC) are a cornerstone of combination therapies for multiple myeloma. However, patients ultimately develop resistance to GCs frequently based on decreased glucocorticoid receptor (GR) expression. An understanding of the direct targets of GC actions, which induce cell death, is expect...
Autores principales: | Thomas, Alexandra L., Coarfa, Cristian, Qian, Jun, Wilkerson, Joseph J., Rajapakshe, Kimal, Krett, Nancy L., Gunaratne, Preethi H., Rosen, Steven T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nuclear Receptor Signaling Atlas
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693629/ https://www.ncbi.nlm.nih.gov/pubmed/26715915 http://dx.doi.org/10.1621/nrs.13006 |
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