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Interleukin‐25 initiates Th2 differentiation of human CD4(+) T cells and influences expression of its own receptor

Human CRTh2(+) Th2 cells express IL‐25 receptor (IL‐25R) and IL‐25 has been shown to potentiate production of Th2 cytokines. However, regulation of IL‐25R and whether it participates in Th2 differentiation of human cells have not been examined. We sought to characterize IL‐25R expression on CD4(+) T...

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Detalles Bibliográficos
Autores principales: Bredo, Graeme, Storie, Jessica, Shrestha Palikhe, Nami, Davidson, Courtney, Adams, Alexis, Vliagoftis, Harissios, Cameron, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693727/
https://www.ncbi.nlm.nih.gov/pubmed/26734466
http://dx.doi.org/10.1002/iid3.87